Clinical Research Applications
The Axela multiplex systems for protein and gene research are ideal tools for clinical researchers in hospitals, medical research institutions, CROs and pharmaceutical companies who are involved in:
- Developing rapid diagnostic assay tests
- Conducting biomarker discovery and validation research
- Developing “Laboratory Developed Tests”
- Medical research including cancer and infectious diseases
- Analyzing a range of analytes within complex biological samples
- Pathogen detection and analysis from crude clinical samples
and who need:
- A simple method to translate discoveries into multiplex assays that allow validation of utility and routine execution
- Rapid results to enable assay development and ultimately clinical decisions
- To conserve valuable sample
- A large dynamic range
- Robustness and reproducibility regardless of location and user
Applications
dotLab mX System
Protein Biomarker Validation
- Multiple biomarker validation with the panelPlus multiplex sensor
- Proven applications in oncology and cardiac diseases
Infectious Diseases
- Automated IgG titer and avidity measurements
- Automated serology assays
- Direct bacteria and virus capture for pathogen detection
Assay Development
- Rapid optimization of antibody ranking and pairing, buffer conditions, and cross reactivity
Analyte Quantitation
- Provides high sensitivity (picomolar level) and dynamic range (>7 logs) without serial dilutions on crude samples
Ziplex System
Translational research
- Transfer of gene expression signatures discovered on global expression assays onto focused arrays for validation and routine analysis
- Protein Biomarker panels using universal panelPlus adressing reagents
Laboratory Developed Tests
- Automated and simple-to-use bench top instrument
Infectious Diseases
- Rapid pathogen (100+) screening on antigen arrays
- On-chip calibration and controls for the robust analysis of serum antibodies
Flexibility
- Same platform for gene and protein expression
The Axela Advantage
- Reproducible, robust results
- Flexibility to customize individual assays
- Minimal sample consumption
- Ability to detect both high and low abundance analytes